Metabonomics in Toxicity Assessment

ISBN: 9780824726652

出版社: Marcel Dekker Inc

出版年: 2005-3

页数: 536

定价: $ 225.94

装帧: HRD

内容简介

Filling a gap in the literature, this reference provides comprehensive coverage of all aspects of metabonomics technology including analytical and biologic considerations, as well as sections on chemometrics-devoting entire chapters to critical topics such as biomarkers, metabolite identification, and the use of magic angle spinning for tissue metabonomics. It includes numerous examples illustrating strategies and techniques for the identification of endogenous and xenobiotic metabolites. Providing essential tools for the toxicologist utilizing metabonomic technologies, this guide presents a clear outline of the use of metabonomics in the safety assessment of new chemical entities.